Rx
🏭 Sanofi
❄️ Cold Chain
⭐ 3 Strains TIV
🌐 WHO SH
🔄 Annual Vaccine
VAXIGRIP® SH PFS · Sanofi Pasteur · 0.5 mL Prefilled Syringe · Intramuscular Injection
3 WHO SH Strains · 15 µg HA each · Inactivated Split Virion · Sanofi India
👥 Who Should Get VAXIGRIP SH PFS?
The influenza vaccine is recommended for everyone 6 months and older annually. VAXIGRIP SH PFS with WHO Southern Hemisphere strains is especially important for:
Children (6 months – 8 years)
Children are at high risk of severe flu complications including pneumonia, hospitalization and febrile seizures. First-time flu vaccine recipients under 9 require 2 doses, 4 weeks apart. Annual vaccination thereafter.
Adults 65+ Years (Elderly)
Elderly individuals are most vulnerable to flu-related deaths. Annual flu vaccination with VAXIGRIP SH PFS reduces risk of hospitalization and pneumonia. Priority group for annual flu vaccination.
Pregnant Women
Safe and recommended in any trimester. Maternal influenza antibodies transfer to the newborn via placenta, protecting babies in their first 6 months. Annual flu vaccination is strongly recommended in pregnancy.
Healthcare Workers
Exposed to influenza patients year-round. Annual flu vaccination protects HCWs and prevents transmission to vulnerable patients. VAXIGRIP SH PFS is widely used in hospital vaccination programmes.
Chronic Disease Patients
Asthma, COPD, heart disease, diabetes, chronic kidney disease, obesity — all significantly increase risk of severe flu complications. Annual vaccination is strongly recommended for all such patients.
Immunocompromised Individuals
HIV, post-transplant, chemotherapy, high-dose steroids — VAXIGRIP SH PFS is safe (no live virus) and essential in immunocompromised individuals. They may need higher-dose or adjuvanted flu vaccines — ask your doctor.
International Travellers
Flu circulates year-round globally. Travel to Southern Hemisphere countries — Australia, South Africa, Argentina — exposes you to SH strains. VAXIGRIP SH PFS provides targeted protection for SH season travel.
Whole Family Vaccination
One VacciHub home visit — vaccinate infants, parents, grandparents together. Reduces household flu transmission. Herd protection within family especially important when vulnerable members (elderly, infants) are present.
🔬 VAXIGRIP SH PFS Composition – Per 0.5 mL Dose
Each 0.5 mL prefilled syringe contains, as per Sanofi manufacturer specifications:
| Component | Quantity | Notes |
|---|---|---|
| ACTIVE INGREDIENTS – 3 INFLUENZA STRAINS (WHO SH SH) | ||
| A/Victoria/4897/2022 (H1N1)pdm09-like (WHO Southern Hemisphere Recommendation) |
15 µg HA | Split virion — virus fragmented by detergent, inactivated |
| A/Croatia/10136RV/2023 (H3N2)-like (WHO Southern Hemisphere Recommendation) |
15 µg HA | Split virion — virus fragmented by detergent, inactivated |
| B/Austria/1359417/2021-like (B/Victoria lineage) (WHO Southern Hemisphere Recommendation) |
15 µg HA | Split virion — virus fragmented by detergent, inactivated |
| PRODUCTION AND INACTIVATION | ||
| Propagation medium | Fertilized hen's eggs | From specific pathogen-free (SPF) chicken flocks |
| Inactivation/splitting method | Formaldehyde + detergent (Triton X-100) | Virus inactivated then split into fragments; HA and NA extracted |
| EXCIPIENTS | ||
| Thimerosal (preservative) | < 50 µg Hg (mercury) per dose or thimerosal-free | Check product label; thimerosal-free prefilled syringe available |
| Sodium chloride, Disodium phosphate, Potassium dihydrogen phosphate | q.s. | Buffered saline solution (PBS) |
| Water for Injections | q.s. to 0.5 mL | Vehicle |
💡 Split Virion Technology: VAXIGRIP SH PFS uses split virion technology — the influenza virus is grown in eggs, inactivated with formaldehyde, then split using a detergent (Triton X-100) into fragments. This creates a vaccine containing the HA, NA and internal viral proteins, providing broader immune stimulation while being safer than whole-virus vaccines. Well tolerated even in children and elderly.
⚠️ Egg allergy note: VAXIGRIP SH PFS is grown in fertilized hen's eggs and may contain trace egg proteins (ovalbumin typically <1 µg/dose). Persons with mild egg allergy (hives only) can receive it under 30-minute post-vaccination observation. Persons with history of severe egg anaphylaxis — consult doctor. VacciHub nurses conduct pre-vaccination health screening before every dose.
📅 VAXIGRIP SH PFS Vaccination Schedule
| Age Group | Number of Doses | Timing | Notes |
|---|---|---|---|
| Children 6 months – 8 years (receiving flu vaccine for the FIRST time) | 2 Doses | Dose 1 + Dose 2 at least 4 weeks apart | First-time only; 1 dose annually thereafter |
| Children 6 months – 8 years (previously vaccinated) | 1 Dose | Once annually before flu season | If 2+ lifetime flu vaccine doses received previously |
| Children 9 years and older + Adults | 1 Dose | Once every year | Single annual dose, every flu season |
| Pregnant Women | 1 Dose | Any trimester · every year | Protects mother and transfers antibodies to newborn |
| Elderly 65+ and high-risk patients | 1 Dose | Annually · before monsoon or winter season | Annual re-vaccination with current season strains is essential |
ℹ️ Best time to vaccinate in India: India has two flu peaks — monsoon (June–September) and winter (November–February). For the Southern Hemisphere formulation: vaccinate before monsoon (April–May) for July–September protection. Annual re-vaccination with the updated formulation is the only way to maintain relevant seasonal protection.
💡 Route of administration: Intramuscular (IM) injection into the deltoid muscle (adults and older children) or anterolateral thigh (infants and toddlers). Our VacciHub certified nurses ensure correct injection technique for all age groups.
⚙️ How Does VAXIGRIP SH PFS Work?
1
Split Virion Antigens Injected Intramuscularly
0.5 mL of VAXIGRIP SH PFS injected IM into the deltoid. The dose delivers fragmented influenza virus particles (split virion) from all 3 WHO SH strains — H1N1, H3N2, and B/Victoria. Each strain contributes 15 µg of Haemagglutinin (HA) antigen. No live virus is present — the vaccine cannot cause influenza.
2
Immune System Recognition and Processing
Antigen-presenting cells (macrophages, dendritic cells) at the injection site engulf the split virion fragments. They process the HA, NA and internal viral proteins, then present antigens on MHC class II receptors to T-helper cells (CD4+), initiating the adaptive immune response against all 3 strains.
3
Strain-Specific Anti-HA Antibodies Generated
B-lymphocytes produce high-titre strain-specific IgG antibodies — primarily anti-HA antibodies targeting H1N1, H3N2 and B/Victoria. These anti-HA antibodies neutralize influenza virus by blocking the HA protein from binding to respiratory epithelial cells, preventing infection from establishing.
4
Seasonal Protection Established in 10–14 Days
Protective antibody levels develop within 10–14 days post-vaccination. Memory B-cells and T-cells provide immune memory. However, antibody levels wane over 6–12 months AND new influenza strains emerge each season — making annual vaccination with the current season formulation essential for continued protection.
✅ Cannot cause flu: VAXIGRIP SH PFS is a completely inactivated, split virion vaccine — no live or attenuated virus whatsoever. It is physiologically impossible to contract influenza from VAXIGRIP SH PFS. Post-vaccination symptoms like mild soreness or low-grade fever are normal immune activation responses, not flu infection.
⚠️ VAXIGRIP SH PFS Side Effects
VAXIGRIP SH PFS has an excellent safety record. Extensive post-marketing surveillance across hundreds of millions of doses globally confirms high tolerability. Most recipients experience no or minimal side effects.
🟡 Very Common and Common (Mild, 1–2 Days)
- 💉 Injection-site pain or soreness
- 🔴 Redness or induration at injection site
- 🤕 Headache (mild)
- 😴 Fatigue or malaise
- 💪 Myalgia (muscle ache)
- 🌡️ Low-grade fever (below 38°C)
🔴 Rare — Seek Medical Attention Immediately
- 🥚 Egg protein allergic reaction
- 😵 Syncope (fainting) post-injection
- ⚡ Guillain-Barré Syndrome (GBS) — extremely rare
- 🚨 Anaphylaxis (extremely rare, 1-2 per million doses)
💡 Post-vaccination care: Remain seated for 15–30 minutes after injection. Apply a cool cloth to the injection site for comfort. Paracetamol (acetaminophen) can be taken for fever or pain per doctor's advice. Avoid vigorous exercise for 24 hours. Our VacciHub nurses monitor all patients post-vaccination before leaving.
⚖️ VAXIGRIP SH PFS vs Other Flu Vaccines Available in India
| Feature | VAXIGRIP SH PFS Sanofi | FLUARIX SH GSK | Influvac Tetra Abbott |
|---|---|---|---|
| Type | Trivalent (TIV) | Trivalent (TIV) | Quadrivalent (QIV) |
| Antigen | Split Virion | Split Virion | Surface Antigen |
| Strains | 3 Strains | 3 Strains | 4 Strains |
| HA per strain | 15 µg | 15 µg | 15 µg |
| Total HA | 45 µg/dose | 45 µg/dose | 60 µg/dose |
| MRP | ₹2,100 | ₹2,100 | ₹2,688 |
| VacciHub Price | ₹1,995 | ₹1,995 | ₹2,554 |
| WHO SH | ✅ Yes | ✅ Yes | ✅ Yes |
| Cold Chain | ✅ Yes | ✅ Yes | ✅ Yes |
ℹ️ Which flu vaccine should I choose? For maximum protection covering both B lineages, choose Influvac Tetra (QIV). For a trusted Sanofi trivalent option at a competitive price, VAXIGRIP SH PFS is excellent. For budget-conscious families, VaxiFlu offers good protection. All 3 are WHO-compliant for current SH season. Consult VacciHub for personalized guidance.
🚫 Precautions and Contraindications
Do NOT give VAXIGRIP SH PFS if:
- Anaphylaxis or severe hypersensitivity to a previous influenza vaccine dose
- Severe anaphylactic hypersensitivity to egg proteins (egg anaphylaxis history)
- Moderate to severe acute febrile illness — defer vaccination until full recovery (mild illness without fever is NOT a contraindication)
Use with Caution — Consult Doctor First:
- Mild egg allergy (hives only) — can receive VAXIGRIP SH PFS with 30-minute post-vaccination observation
- History of Guillain-Barré Syndrome (GBS) within 6 weeks of previous influenza vaccination
- Severe immunosuppression — vaccine may produce reduced antibody response but is still recommended
- Bleeding disorders or anticoagulant therapy — inform VacciHub nurse before vaccination
⚠️ Storage requirements: VAXIGRIP SH PFS must be stored at 2°C to 8°C. Do NOT freeze. Protect from light. VacciHub nurses transport VAXIGRIP SH PFS in validated cold-chain boxes with temperature data loggers to ensure 2–8°C compliance from our storage to your home.
🏥 Why Book VAXIGRIP SH PFS with VacciHub?
Certified Nursing Staff
Trained, certified nurses for all age groups — infants (6 months+) to elderly (100+). Correct IM injection technique. Pre-vaccination health check and history review included with every home visit.
End-to-End Cold Chain
VAXIGRIP SH PFS transported in validated cold boxes at 2–8°C. Never frozen. Temperature data logged. Full cold chain compliance certificate available on request. Potency guaranteed.
Genuine Sanofi VAXIGRIP SH PFS
Sourced exclusively from authorised Sanofi distributors. current SH season formulation confirmed. Batch number and expiry date shared on WhatsApp receipt post-vaccination.
Whole Family in One Visit
Vaccinate the whole family — infants, parents, grandparents — in a single home visit. No hospital trips or waiting. Significant cost saving on nursing fee for multi-dose visits.
Annual Flu Reminder Service
WhatsApp reminder set automatically for next year's flu shot. Never miss a season. Annual vaccination tracking maintained for your family records on request.
Same-Day and Weekend Slots
Flexible bookings morning to evening, 7 days a week including public holidays. Need flu vaccination before travel or before monsoon? Same-day appointments available.
📍 VAXIGRIP SH PFS Home Vaccination – Cities We Serve
🏛️Delhi (All Areas)
🏙️Gurgaon
🌆Noida
🏘️Ghaziabad
🏗️Faridabad
🌇Greater Noida
Call +91 92050 04114 to confirm service availability for your specific pincode — same-day slots available in most areas.
❓ Frequently Asked Questions – VAXIGRIP SH PFS
VAXIGRIP SH PFS is an Inactivated Influenza Vaccine (Split Virion) manufactured by Sanofi Pasteur, one of the world's leading pharmaceutical companies. The "SH" indicates it contains WHO Southern Hemisphere recommended strains. It protects against 3 influenza strains: H1N1, H3N2, and B/Victoria lineage, each at 15 µg HA per dose.
VAXIGRIP SH PFS MRP is ₹2,100 per dose. VacciHub offers it at ₹1,995 per dose (5% OFF). The nurse home visit fee depends on your pincode area. Call +91 92050 04114 or WhatsApp for the total cost including nurse visit for your location. Multi-dose family visits get the nurse fee shared across doses.
The key difference: VAXIGRIP SH PFS is a Trivalent (3-strain) vaccine covering H1N1, H3N2 and B/Victoria lineage. Influvac Tetra is a Quadrivalent (4-strain) vaccine additionally covering B/Yamagata lineage. For maximum coverage against both B lineages, Influvac Tetra provides broader protection. VAXIGRIP SH PFS uses split virion technology while Influvac Tetra uses surface antigen (more purified). Both are excellent choices — Influvac Tetra offers an extra layer of B-strain protection. Call us to choose the best option for your family.
Influenza vaccination is required every year for two reasons: (1) Influenza viruses mutate rapidly — each year's circulating strains may differ from the previous year's vaccine strains; (2) Antibody levels from the flu vaccine wane over 6–12 months. Annual vaccination with the current season formulation (WHO SH SH) is the only way to maintain relevant and effective protection against circulating flu strains.
Yes. VAXIGRIP SH PFS is approved for use from 6 months of age onwards. It is safe and recommended for:
• Children (6 months to 8 years — first-timers get 2 doses; thereafter 1 annual dose)
• Pregnant women — any trimester (recommended by WHO, IAP, ACOG)
• Elderly 65+ — high priority group for annual flu vaccination
• Immunocompromised patients — safe (no live virus), though response may be reduced
Our VacciHub nurses are trained for paediatric, elderly and pregnancy vaccinations.
• Children (6 months to 8 years — first-timers get 2 doses; thereafter 1 annual dose)
• Pregnant women — any trimester (recommended by WHO, IAP, ACOG)
• Elderly 65+ — high priority group for annual flu vaccination
• Immunocompromised patients — safe (no live virus), though response may be reduced
Our VacciHub nurses are trained for paediatric, elderly and pregnancy vaccinations.
Yes. VacciHub provides home vaccination with VAXIGRIP SH PFS across Delhi (all areas), Gurgaon, Noida, Ghaziabad, Faridabad and Greater Noida. A certified nurse comes to your home with genuine Sanofi VAXIGRIP SH PFS at 2–8°C cold chain. Whole family can be vaccinated in one visit. Call +91 92050 04114 or WhatsApp to book your appointment.
The WHO issues annual strain recommendations separately for the Northern Hemisphere (NH) and Southern Hemisphere (SH). India's flu seasons partially overlap with the Southern Hemisphere pattern (monsoon peak: July–September). VAXIGRIP SH PFS is formulated with WHO Southern Hemisphere strains — H1N1 (A/Victoria), H3N2 (A/Croatia) and B/Victoria — specifically selected by WHO for optimal protection against strains expected to circulate in current SH season.
A split virion influenza vaccine (like VAXIGRIP SH PFS) is made by growing influenza virus in fertilized hen's eggs, inactivating it with formaldehyde, then using a detergent (Triton X-100) to split the virus into fragments. The resulting vaccine contains the HA and NA proteins plus internal viral proteins. Compared to whole-virus vaccines, split virion vaccines cause fewer side effects. Compared to surface antigen vaccines (like Influvac Tetra), split virions include more viral components which may stimulate broader cellular immunity in some populations.